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Showing posts with the label Haematology

Anaemias and Bleeding Disorders

Anaemia: Most common problem in medical clinics the world over. Major public Health importance Chronic disability Poor quality of life Low income

Medical Significance of Rhesus Negative Factor (Rh -). A Must Read

Rhesus Factor is an antigen that exists on the surface of red blood cells in most people (about 85% of humans). It is also referred to as Rh Factor. People who have the Rh factor have “positive” (+) blood types, such as A+, O+ or B+ while those who do not have the Rh factor have “negative” (-) blood types, such as A–, O– or AB– .

Hypercoagulation and Bleeding Disorders: Definitions, Causes, Diagnosis and Treatments.

Blood Coagulation can be simply defined as the process at which blood forms clot. When there is  a vascular injury, the platelets clump together and stick to the edges of the damaged vessel. They  release substances into the blood that perform a variety of functions:

Stem Cell Therapy and Its Significance!

Stem Cell Therapy comes in different types. Embryonic Stem Cell Therapy involves the use of embryonic stem cells derived from the inner cell mass of a blastocyst, an early-stage pre-implantation embryo at 4 days old to around 12 days old, leading to the destruction of the blastocyst which raises ethical and religious issues. Therefore, this type of Stem Cell Therapy is not the focus of this piece.  The focus is Adult Stem Cells (ADSCs) and Induced Pluripotent Stem Cells (iPSCs). iPSCs are produced in the laboratories by

Laboratory Control of Anticoagulants, Thrombolytic and Anti-Platelet Therapy.

INTRODUCTION Anticoagulants are classes of drugs that work to prevent coagulation (clotting) of blood. They can be used in-vivo as a medication for thrombotic disorders. Some are also used in medical equipment such as test tubes, blood transfusion bags and renal dialysis. Thrombosis  is the formation of a blood clot (thrombus) inside a blood vessel, obstructing the flow of blood through the circulatory system.


A test is performed in other to determine the structure, shape, color and pattern appearances of the different blood cells present in the blood. i.e red cells, white cell, platelets. BLOOD FILM? Is a thin layer of blood smeared on a microscopic slide and then stained in such a way to allow the various blood cells to be examined microscopically. FIXING When completely dry, fix a blood film with absolute  methanol. Place the film on a staining rack and add 1-2 drops of moisture free methy alcohol and allow to dry on the film. STAINING THE BLOOD FILM In district laboratories, thin blood films are usually stained manually using leishman or wright’s stain. These stains are example of alcohol containing romanowsky stains which stain blood cells differently, making it possible for the scientist to differentiate and identify the various blood cells.